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在小鼠基因组结构变异的基于序列的表征

Binnaz Yalcin1, Kim Wong, Avigail Agam

  • 1The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

Nature
|September 17, 2011
PubMed
概括

结构变异 (SVs) 在小鼠基因组中很常见,反转移子插入是主要原因. 尽管SVs繁多,但它们很少影响基因表达或表型,尽管有些人会破坏基因功能,特别是在免疫学中.

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