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卡斯帕斯-8调节TNF-α诱导的上皮细胞亡和终端炎

Claudia Günther1, Eva Martini, Nadine Wittkopf

  • 1Department of Medicine 1, Friedrich-Alexander-University, D-91054 Erlangen, Germany.

Nature
|September 17, 2011
PubMed
概括

肠上皮细胞 (IEC) 中的卡斯帕-8 缺乏会引发亡,从而导致小鼠的帕内斯细胞损失和终端炎. 这表明由RIP3驱动的亡可能在克罗恩氏病中发挥作用.

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