1980年至2010年间,187个国家的乳腺癌和宫癌:系统分析
Mohammad H Forouzanfar1, Kyle J Foreman, Allyne M Delossantos
1Institute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Lancet (London, England)
|September 20, 2011
概括
全球乳腺癌发病率正在上升,而宫癌的发病率正在下降. 这两种癌症仍然是导致死亡的重要原因,特别是在发展中国家,需要增加政策重点.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 乳腺癌和子宫癌是全球15岁及以上女性死亡的主要原因.
- 在187个国家进行了年度年龄特定评估.
研究的目的:
- 从1980年到2010年,分析乳腺癌和宫癌发病率和死亡率的全球趋势.
- 为癌症负担提供特定年龄和特定国家的估计.
主要方法:
- 系统地收集癌症登记数据,生命记录和口头尸检数据.
- 使用等级模型对死亡率与发病率 (MI) 的建模.
- 高斯过程回归用于估计死亡率和发病率的不确定性.
主要成果:
- 从1980年到2010年,全球乳腺癌发病率每年上升3.1%. 乳腺癌在2010年造成4.25万例死亡.
- 全球宫癌发病率每年增加0.6%,导致2010年有20万例死亡. 死亡率正在下降.死亡率正在下降.
- 观察到乳腺癌死亡率趋势的区域差异很大. 发展中国家承担着相当大的负担,尤其是对年轻女性来说.
结论:
- 增加政策关注对于加强卫生系统对乳腺癌和宫癌的反应至关重要.
- 发展中国家特别需要有针对性的干预措施,以减少癌症死亡率.
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