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Updated: May 29, 2026

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
12:43

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE

Published on: July 29, 2014

通过先天性免疫受体RIG-I进行RNA识别和激活的结构基础

Fuguo Jiang1, Anand Ramanathan, Matthew T Miller

  • 1Center for Advanced Biotechnology and Medicine, Department of Chemistry and Chemical Biology, Rutgers University, 679 Hoes Lane West, Piscataway, New Jersey 08854, USA.

Nature
|September 28, 2011
PubMed
概括

网红酸诱导基因-I (RIG-I) 识别病毒RNA以启动天生的免疫力. 它的结构揭示了螺旋酶和抑制子域如何结合双链RNA,这对抗病毒防御至关重要.

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