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Updated: May 22, 2026

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酶性甲基转移:活性位点残留物在产生活性位点缩中的作用与催化效率相关

Jianyu Zhang1, Judith P Klinman

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|October 1, 2011
PubMed
概括

人类甲基转移酶 (COMT) 酶的活性与活性部位的紧缩有关. 突变显示了催化效率和动态同位素效应之间的相关性,影响了多巴胺代谢.

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