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Julian Lange1, Jing Pan, Francesca Cole

  • 1Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.

Nature
|October 18, 2011
PubMed
概括

通过抑制SPO11活动,ATM激酶在半分裂过程中抑制双链断裂 (DSB) 的形成. 这种负反循环可以防止过度的DSBs,这对于防止介质错误和生殖腺失调至关重要.

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