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通过复制合释放RNA Pol II的RNAi促进异色沉默

Mikel Zaratiegui1, Stephane E Castel, Danielle V Irvine

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

Nature
|October 18, 2011
PubMed
概括

在细胞分裂过程中,RNA干扰 (RNAi) 对于维持异染色素至关重要. 在裂变酵母中,共转录RNAi解决了转录和复制之间的冲突,确保了适当的异染色质蛋白遗传.

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Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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