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通过Mre11和Exo1进行DNA双链断裂的双向切除

Valerie Garcia1, Sarah E L Phelps, Stephen Gray

  • 1Genome Damage and Stability Centre, The University of Sussex, Brighton, BN1 9RQ, UK.

Nature
|October 18, 2011
PubMed
概括

这项研究表明,Mre11外核酶通过使双向切除成为可能,在DNA双链断裂修复中起着至关重要的作用. 这一过程对于有效的DNA修复至关重要,并赋予了对DNA损伤的抵抗力.

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