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Updated: May 28, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
06:09

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

一个SUMOylation缺陷的MITF生殖基因突变会导致黑色素瘤和癌的发生

Corine Bertolotto1, Fabienne Lesueur, Sandy Giuliano

  • 11] INSERM, U895 (équipe 1), Equipe labélisée Ligue Contre le Cancer, C3M, 06204 Nice, France [2] Université of Nice Sophia-Antipolis, UFR Médecine, 06204 Nice, France [3] Centre Hospitalier Universitaire de Nice, Service de Dermatologie, 06204 Nice, France [4].

Nature
|October 21, 2011
PubMed
概括

微相关转录因子 (MITF) 基因的基因变异Mi-E318K显著增加患黑色素瘤和细胞癌 (RCC) 的风险. 这一发现表明,这两种癌症具有共同的遗传倾向.

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