Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: May 28, 2026

Real-time In Vivo Recording of Arabidopsis Calcium Signals During Insect Feeding Using a Fluorescent Biosensor
08:21

Real-time In Vivo Recording of Arabidopsis Calcium Signals During Insect Feeding Using a Fluorescent Biosensor

Published on: August 15, 2017

一个新的高度选择性的光K+传感器.

Xianfeng Zhou1, Fengyu Su, Yanqing Tian

  • 1Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, USA.

Journal of the American Chemical Society
|October 27, 2011
PubMed
概括
此摘要是机器生成的。

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Pharmacokinetics, safety, and efficacy of fuzuloparib in combination with abiraterone acetate and prednisone in patients with metastatic castration-resistant prostate cancer: a phase 1 dose escalation and expansion study.

BMC cancer·2026
Same author

Coxsackievirus A6 on the rise: epidemiology, pathogenicity, evolutionary dynamics, and antiviral strategy.

Clinical microbiology reviews·2026
Same author

Targeted sequence capture of coxsackievirus A6 using nanopore sequencing directly from clinical specimens.

Microbiology spectrum·2026
Same author

Prophylactic Central Lymph Node Dissection Versus Thyroidectomy Alone in Clinically Node-Negative Thyroid Cancer: A Systematic Review and Meta-Analysis.

Ear, nose, & throat journal·2026
Same author

Kinetically Gated and Self-Limiting Crystallization Enables Allosteric Phototheranostic Nanocrystals.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Need for gender-neutral human papillomavirus vaccination: Lessons from a retrospective epidemiologic investigation of human papillomavirus infections among outpatients presenting to a tertiary dermatology hospital in Central China from 2017 to 2024.

IJID regions·2026
Same journal

Radical Cascades on Seawater Microdroplets Drive Atmospheric Mercury Oxidation.

Journal of the American Chemical Society·2026
Same journal

Superior Selective and Fast NH<sub>3</sub> Adsorption of Soft Porous MOF/Ionic Liquid Composites with Ordering Phase Transitions.

Journal of the American Chemical Society·2026
Same journal

Systematic Catalyst Variation for Improved Stereoselective Epoxide Polymerization: Subtle Modifications Resulting in Superior Efficiency.

Journal of the American Chemical Society·2026
Same journal

Deciphering the Halide Chemistry of Cl<sup>-</sup> and Br<sup>-</sup> in Enhancing Kinetics of Mg Plating/Stripping.

Journal of the American Chemical Society·2026
Same journal

Electrosynthesis of C<sub>6</sub> Chemicals by Propylene Oxidative Coupling on Au Surface.

Journal of the American Chemical Society·2026
Same journal

Statistical AI Enables Precise Screening of Multielement Catalysts.

Journal of the American Chemical Society·2026
查看所有相关文章

一种新的光传感器KS2能够在广泛的度范围内进行高度选择性的细胞内 (K+) 检测. 这一突破对于理解细胞过程和诊断癌症等疾病至关重要.

科学领域:

  • 化学传感器是一种化学传感器.
  • 分子成像学分子成像学
  • 生物医学诊断 生物医学诊断

背景情况:

  • 离子 (K+) 在细胞功能中起着至关重要的作用.
  • 精确的细胞内K+监测对于了解细胞健康和疾病至关重要.
  • 现有的传感器往往缺乏选择性或在有限的度范围内工作.

研究的目的:

  • 开发和描述一种新的光化学传感器KS2,用于敏感和选择性的细胞内离子 (K+) 检测.
  • 为了评估传感器在活细胞中的性能,在广泛和高度范围内.
  • 为了证明KS2对细胞成像和疾病诊断的实用性.

主要方法:

  • 合成了KS2光化传感器,其中包括一个triazacryptand连接体和一个2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) 取电子组.
  • 描述KS2的光物理特性和对不同K+度的反应.
  • 在共聚焦光显微镜中应用KS2用于活细胞K+成像.

主要成果:

  • KS2对高达1.6M的K+有强烈的反应,证明了其对高度传感的能力.
  • 传感器显示K+离子的高选择性,使其与其他生物学相关的离子区别开来.

更多相关视频

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
08:27

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer

Published on: October 1, 2016

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
10:07

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

Published on: January 27, 2013

相关实验视频

Last Updated: May 28, 2026

Real-time In Vivo Recording of Arabidopsis Calcium Signals During Insect Feeding Using a Fluorescent Biosensor
08:21

Real-time In Vivo Recording of Arabidopsis Calcium Signals During Insect Feeding Using a Fluorescent Biosensor

Published on: August 15, 2017

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
08:27

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer

Published on: October 1, 2016

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
10:07

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

Published on: January 27, 2013

  • 同焦光显微镜成功地使用KS2在活细胞中可视化了细胞内K+水平.

    • 结论:

    • KS2是第一个高度选择性的细胞内传感器,可以在广泛和高度范围内检测K+.
    • 传感器能够执行活细胞K+成像的能力为研究开辟了新的途径.
    • KS2具有研究细胞代谢,诊断癌症等疾病和监测治疗反应的巨大潜力.