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Updated: May 28, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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通过使用基于结构的理性设计来增加艾滋病毒抗体的效力和范围

Ron Diskin1, Johannes F Scheid, Paola M Marcovecchio

  • 1Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

Science (New York, N.Y.)
|October 29, 2011
PubMed
概括

针对CD4结合部位的强有力的HIV-1抗体被设计出来. 结构洞察力揭示了增强中和范围和效力的修改,指导未来免疫原体设计有效的HIV-1疫苗.

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