在酵母菌中Aβ毒性,内细胞贩运和阿尔茨海默病风险因素之间的功能联系

Sebastian Treusch1, Shusei Hamamichi, Jessica L Goodman

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|October 29, 2011
PubMed
概括

在酵母中研究了β-粉样 (Aβ) 毒性,这是阿尔茨海默病 (AD) 的关键因素. 研究人员确定了新的内细胞通路因素,这些因素改变了酵母,虫和老鼠神经元中的Aβ毒性.

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