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Updated: May 28, 2026

High-Resolution Neutron Spectroscopy to Study Picosecond-Nanosecond Dynamics of Proteins and Hydration Water
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用溶液NMR探测的粉样β原纤维的表面上的原子分辨率动态

Nicolas L Fawzi1, Jinfa Ying, Rodolfo Ghirlando

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0520, USA.

Nature
|November 1, 2011
PubMed
概括

一种新的NMR技术,暗态交换和转移 (DEST),揭示了与原纤维素的粉样蛋白β (Aβ) 单体交换的原子级细节. 这有助于我们更好地了解阿尔茨海默病的机制和Aβ聚合.

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