相关实验视频
Updated: May 12, 2026

09:36
Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
Published on: October 17, 2010
成年期中适度饮酒,饮酒习惯,以及乳腺癌风险
Wendy Y Chen1, Bernard Rosner, Susan E Hankinson
1Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA. wendy.chen@channing.harvard.edu
JAMA
|November 3, 2011
概括
即使低饮酒量也会增加乳腺癌的风险,特别是在饮酒过度的饮酒模式下. 整个成年期累积的酒精摄入量是一个关键因素,无论何时发生.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 酒精消费与增加乳腺癌风险之间的确立联系.
- 与较低的酒精摄入量水平相关的风险的有限量化.
- 饮酒模式和成年期饮酒时间的不清楚影响.
研究的目的:
- 评估乳腺癌与成年人一生中饮酒量之间的关系.
- 分析酒精数量,饮酒频率和饮酒年龄对乳腺癌风险的影响.
- 量化与低水平饮酒相关的风险.
主要方法:
- 一项前性观察性研究,包括来自护士健康研究 (1980-2008) 的105,986名女性.
- 使用了早期成人酒精评估,并在随访期间更新了8项评估.
- 监测开发侵袭性乳腺癌的相对风险.
主要成果:
- 即使在低消费水平 (5.0-9.9克/天) 中,也观察到乳腺癌风险的统计显著增加.
- 过度饮酒,独立于累积摄入量,与更高的乳腺癌风险有关.
- 早期和晚年成年期的酒精消费独立地导致风险增加.
结论:
- 低饮酒量与乳腺癌风险的适度增加有关.
- 成年期累积的酒精摄入量是乳腺癌的重要预测因素.
- 不同生命阶段的酒精消费独立影响乳腺癌风险.
相关概念视频
Longitudinal Research
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Hypothesis Test for Test of Independence
The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
H0: The two variables (factors)...
Stress Prevention and Stress Management Techniques IV
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
Psychoneuroimmunology: Diabetes and Cancer
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

