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重新设计一个基酶以优先化一个直接的化物前体

Weslee S Glenn1, Ezekiel Nims, Sarah E O'Connor

  • 1Department of Biological Chemistry, The John Innes Centre, Norwich NR4 7UH, UK.

Journal of the American Chemical Society
|November 5, 2011
PubMed
概括

工程设计的黄素依赖素酶RebH (Y455W) 选择性地化胺,类化合物的前体. 这种工程酶能够在体内产生基化物,而不会在植物中积累不必要的副产品.

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