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Updated: May 27, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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耐水解3'-基-tRNA模仿物的原生化学结合

Anna-Skrollan Geiermann1, Norbert Polacek, Ronald Micura

  • 1Institute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Austria.

Journal of the American Chemical Society
|November 5, 2011
PubMed
概括

合成耐水解3'-基RNA模仿tRNA终端,即使是复杂的氨基酸如氨酸,现在是高效的. 这种新的方法使用固相合成和原生化学结合来获得高纯度的-RNA合物.

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Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...