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Nanomanipulation of Single RNA Molecules by Optical Tweezers
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快速和缓慢:折叠和捕捉 λ6-85 的

Maxim B Prigozhin1, Martin Gruebele

  • 1Department of Chemistry and Center for Biophysics and Computational Biology, University of Illinois, Urbana, Illinois 61801, USA.

Journal of the American Chemical Society
|November 10, 2011
PubMed
概括

快速的蛋白质折叠可以隐藏缓慢的运动阶段,正如在兰巴抑制器碎片研究中所见. 虽然野生类型的蛋白质快速折叠,但稳定的突变物和变质条件显示出毫秒陷,表明对粉样蛋白形成的动力保护.

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