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Updated: May 27, 2026

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脂肪细胞NCoR淘汰会降低PPARγ的酸化,并增强PPARγ活性和胰岛素敏感性

Pingping Li1, Wuqiang Fan, Jianfeng Xu

  • 1Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

Cell
|November 15, 2011
PubMed
概括

核受体核心压缩器 (NCoR) 在脂肪细胞中的淘汰改善了肥胖小鼠的葡萄糖耐受性和胰岛素敏感性. 删除NCoR可以减少炎症并增强脂肪细胞功能,模仿糖尿病药物的效果.

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