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Updated: May 27, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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在MITF中出现的一种新型复发性突变会导致家族性和零星性黑色素瘤的发生

Satoru Yokoyama1, Susan L Woods, Glen M Boyle

  • 1Department of Dermatology, Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Massachusetts 02114, USA.

Nature
|November 15, 2011
PubMed
概括

研究人员发现了一种新的基因变异,微相关转录因子 (MITF) E318K,与家族黑色素瘤风险有关. 这一发现突出了全基因组测序的重要意义.

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