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Microfluidics in Assessing Platelet Function
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根据CYP2C19基因型和对稳定心血管疾病患者血小板活性的影响,根据克洛皮多格勒的剂量

Jessica L Mega1, Willibald Hochholzer, Andrew L Frelinger

  • 1TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA. jmega@partners.org

JAMA
|November 18, 2011
PubMed
概括

较高的克洛皮多格勒剂量可以改善CYP2C19*2异构细胞的抗血小板反应. 将剂量增加三倍,达到每日225毫克,使血小板活性正常化,但即使在300毫克的剂量中,同胞细胞也表现出有限的反应.

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