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Updated: May 12, 2026

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Published on: October 5, 2012

FBXO11针对BCL6进行降解,并且在扩散的大B细胞淋巴瘤中被禁用

Shanshan Duan1, Lukas Cermak, Julia K Pagan

  • 1Department of Pathology, NYU Cancer Institute, New York University School of Medicine, New York, New York 10016, USA.

Nature
|November 25, 2011
PubMed
概括

FBXO11的失活导致BCL6的稳定,促进扩散型大B细胞淋巴瘤 (DLBCL) 的发展. 恢复FBXO11抑制DLBCL细胞增殖和瘤性,确定FBXO11是一种瘤抑制剂.

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