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希斯H2B的GlcNAcylation促进了它的单双化

Ryoji Fujiki1, Waka Hashiba, Hiroki Sekine

  • 1Institute of Molecular and Cellular Biosciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

Nature
|November 29, 2011
PubMed
概括

由O-GlcNAc转移酶 (OGT) 在S112中对基因素H2B的O-链接N-乙糖胺 (GlcNAc) 修饰促进了H2B的无处不在. 这种GlcNAcylation将葡萄糖水平与染色质调节和基因转录联系起来.

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