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Updated: May 5, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
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聚合体抑制的基因具有允许增强剂,可以启动重编程

Phillippa C Taberlay1, Theresa K Kelly, Chun-Chi Liu

  • 1Department of Urology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Cell
|December 14, 2011
PubMed
概括

增强剂通过激活关键调节基因,在细胞命运重编程中发挥关键作用. 这些被H3K4me1标记的增强剂产生核细胞贫乏区域,促进转录调节器结合和染色质变化.

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