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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
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选择性核糖体分析揭示了活体中触发因子的共翻译伴侣作用

Eugene Oh1, Annemarie H Becker, Arzu Sandikci

  • 1Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|December 14, 2011
PubMed
概括

研究人员开发了一种新的核糖体分析方法来追踪蛋白质加工因子. 研究表明,触发因子 (TF) 主要与外膜蛋白结合,并在~100个氨基酸被翻译后参与核糖体,从而挑战了先前的模型.

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