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Updated: May 26, 2026

Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach
11:11

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Published on: February 21, 2019

坦基拉斯对基质识别的结构基础和序列规则解释了基路比症疾病的基础

Sebastian Guettler1, Jose LaRose, Evangelia Petsalaki

  • 1Centre for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

Cell
|December 14, 2011
PubMed
概括

研究人员发现了坦基拉酶酶 (TNKS/TNKS2) 的约束规则,这些酶对蛋白质调节至关重要,并且与基路伯有关. 这一发现澄清了坦基酶如何识别基质,并解释了疾病突变.

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Studying Protein Function and the Role of Altered Protein Expression by Antibody Interference and Three-dimensional Reconstructions11:57

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Published on: April 21, 2016

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