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Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
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在单个部位分离酵母和大肠杆菌基因组

M Koob1, W Szybalski

  • 1McArdle Laboratory for Cancer Research, University of Wisconsin, Madison 53706.

Science (New York, N.Y.)
|October 12, 1990
PubMed
概括

研究人员开发了阿基里斯后跟裂解 (AC) 方法,以精确地切割特定位置的酵母和大肠杆菌等大型基因组. 这种技术为基因组映射和分子解剖提供了新的工具.

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