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Updated: May 26, 2026

Reconstruction of the Blood-Brain Barrier In Vitro to Model and Therapeutically Target Neurological Disease
06:19

Reconstruction of the Blood-Brain Barrier In Vitro to Model and Therapeutically Target Neurological Disease

Published on: October 20, 2023

神经科学. 神经科学. 血脑屏障分化的区别

Britta Engelhardt1

  • 1Theodor Kocher Institute, University of Bern, Bern, Switzerland. bengel@tld.unibe.ch

Science (New York, N.Y.)
|December 24, 2011
PubMed
概括

No abstract available in PubMed .

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The Blood-brain Barrier00:49

The Blood-brain Barrier

Overview
Physiological Barriers01:25

Physiological Barriers

Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...