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CYP2C19基因型,克洛皮多格雷尔代谢,血小板功能和心血管事件:系统性审查和元分析

Michael V Holmes1, Pablo Perel, Tina Shah

  • 1Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, 1-19 Torrington Pl, London, WC1E 6BT, United Kingdom. mvholmes@gmail.com

JAMA
|December 29, 2011
PubMed
概括

CYP2C19基因型检测可能会影响克洛皮多格雷尔的反应,但这次系统性审查没有发现与心血管事件有显著的关联. 对基因型导向抗血小板治疗的证据仍然不足以广泛临床使用.

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