化学灵长类动物:胚胎干细胞不需要应用
Alan Trounson1, Uta Grieshammer
1California Institute for Regenerative Medicine, 210 King Street, San Francisco, CA 94107, USA. atrounson@cirm.ca.gov
Cell
|January 10, 2012
概括
研究人员创造了第一个 rhesus 金像. 在非人类灵长类动物中,这一突破是通过聚合四细胞胚胎而不是注射胚胎干细胞来实现的.
科学领域:
- 发育生物学是发展生物学.
- 灵长类动物研究研究.
- 干细胞生物学 干细胞生物学
背景情况:
- 产生可活的嵌合体对于研究早期发育和疾病建模至关重要.
- 以往使用胚胎干细胞制造非人类灵长类木乃伊的尝试一直没有成功.
- 常规情况下,通过将胚胎干细胞注入胚胎囊中来产生老鼠嵌合体.
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