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Updated: May 26, 2026

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结合共抑制剂和伊诺西四酸盐的HDAC3的结构

Peter J Watson1, Louise Fairall, Guilherme M Santos

  • 1Henry Wellcome Laboratories of Structural Biology, Department of Biochemistry, University of Leicester, Leicester LE1 9HN, UK.

Nature
|January 11, 2012
PubMed
概括

基因组脱乙酶 (HDACs) 是癌症的关键目标. 研究人员发现,一种伊诺西四酸盐分子作为分子剂,使HDAC3和共同抑制剂复合体形成,用于基因调节.

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