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一个分子信号灯用于核酸的比度传感

Junchen Wu1, Ying Zou, Chunyan Li

  • 1Institute for Organic Chemistry, University of Duisburg-Essen, 45117 Essen, Germany.

Journal of the American Chemical Society
|January 17, 2012
PubMed
概括

一种新型的信号高效地与双链DNA结合,在结合时改变其光. 这种是细胞透的,使得活细胞内的核酸成像成为可能.

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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