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格雷姆林在肺高血压的发病过程中发挥着关键作用

Edwina Cahill1, Christine M Costello, Simon C Rowan

  • 1University College Dublin, School of Medicine and Medical Sciences, Belfield, Dublin 4, Ireland.

Circulation
|January 17, 2012
PubMed
概括

肺部增加的格雷姆林素有助于慢性低氧性肺部疾病中的肺高血压. 降低格雷姆林的水平可以改善骨形态遗传蛋白 (BMP) 信号传递,减弱血管重塑,提供潜在的治疗点.

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