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相关概念视频

Gastrulation01:56

Gastrulation

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
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Pedigree Analysis01:35

Pedigree Analysis

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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Commitment is the  process whereby stem cells:
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Karyotyping01:17

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Gene Duplication and Divergence02:37

Gene Duplication and Divergence

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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
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相关实验视频

Updated: Nov 6, 2025

Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain
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Lineage Tracing of Inducible Fluorescently-Labeled Stem Cells in the Adult Mouse Brain

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谱系追踪 谱系追踪 谱系追踪

Kai Kretzschmar1, Fiona M Watt

  • 1Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.

Cell
|January 24, 2012
PubMed
概括
此摘要是机器生成的。

血统追踪可以识别所有细胞后代,这对于理解组织发育和疾病至关重要. 先进的技术为研究干细胞生物学和信号通路提供了新的途径.

科学领域:

  • 发展生物学 发展生物学
  • 干细胞生物学 干细胞生物学
  • 哺乳动物组织研究研究

背景情况:

  • 血统追踪起源于19世纪的无脊椎动物研究,现在对成年哺乳动物组织研究至关重要.
  • 它有助于理解组织发育,平衡和疾病过程.
  • 将血统追踪与对细胞命运信号的实验性操纵相结合,提高了它的实用性.

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