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突变的p53通过梅瓦酸途径破坏了乳腺组织结构

William A Freed-Pastor1, Hideaki Mizuno, Xi Zhao

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Cell
|January 24, 2012
PubMed
概括

突变的p53驱动乳腺癌,通过上调调节甲基酸路径,改变细胞结构. 用他类药物准这种途径为p53突变瘤提供了潜在的治疗策略.

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