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Updated: May 25, 2026

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Published on: February 3, 2012

凯尔奇样3和库林3中的突变会导致高血压和电解质异常

Lynn M Boyden1, Murim Choi, Keith A Choate

  • 1Department of Genetics and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

Nature
|January 24, 2012
PubMed
概括

在KLHL3或CUL3基因的突变导致类型II (PHAII),高血压综合征的Pseudohypoaldosteronism. 这些基因对血压和电解质平衡至关重要, thiazide利尿剂可以逆转疾病特征.

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