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通过蛋白质的化学合成实现的向二维基基因酶

Shimrit Ohayon1, Liat Spasser, Amir Aharoni

  • 1Department of Chemistry, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.

Journal of the American Chemical Society
|January 28, 2012
PubMed
概括

研究人员开发了一种新的基于FRET的测定方法,用于选二维基化酶 (DUB) 抑制剂. 这项测试确定了UCH-L3的强有力的抑制剂,有助于对DUB相关疾病的药物发现.

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