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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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在因特因前体中的催化半氨酸之间存在分子内二硫化键

Wen Chen1, Lingyun Li, Zhenming Du

  • 1Department of Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.

Journal of the American Chemical Society
|January 28, 2012
PubMed
概括

研究人员在Pyrococcus abyssi PolII中发现了一种抑制蛋白质拼接的二硫化键. 降解剂打破了这种键,使拼接成为可能,并建议对整体功能的氧化还原控制.

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