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在胚胎干细胞分化过程中,由LSD1关闭增强剂.

Warren A Whyte1, Steve Bilodeau, David A Orlando

  • 1Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

Nature
|February 3, 2012
PubMed
概括

氨酸特异性去甲基酶1 (LSD1) 对于细胞分化至关重要. 这种组质脱甲酶是NuRD复合体的一部分,沉默关键增强剂,使胚胎干细胞从胚胎干细胞状态过渡到专门细胞类型.

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