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Updated: May 25, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
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15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale

Published on: April 19, 2021

通过使用侧链1H探头使用CPMG放松分散NMR量化蛋白质中的毫秒交换动态

Alexandar L Hansen1, Patrik Lundström, Algirdas Velyvis

  • 1Department of Molecular Genetics, The University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Journal of the American Chemical Society
|February 4, 2012
PubMed
概括

这项研究引入了一种新方法,使用标记的蛋白质来测量蛋白质侧链中的千秒化学交换. 这种技术克服了以前的局限性,使得蛋白质动态的结构研究更加详细.

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