概括
对于急性肺损伤患者,初始的热带肠道养没有改善无呼吸器日或死亡率. 然而,与全肠养相比,这种方法减少了胃肠道不耐受症.
科学领域:
- 关键护理医学 关键护理医学
- 肺部医学 肺部医学
- 营养支持营养支持
背景情况:
- 对急性肺损伤 (ALI) 患者的最佳肠道营养策略尚不清楚.
- 确定适当的肠道食初始量对于患者的治疗结果至关重要.
研究的目的:
- 在ALI患者中,比较初始体积较低的热带肠道养与初始全肠道养的疗效.
- 评估对无呼吸器日和胃肠道 (GI) 并发症的影响.
主要方法:
- 该EDEN研究是一项随机的,开放的多中心试验,涉及1000名患有需要机械通风的ALI的成年人.
- 参与者被分配到第一个6天的热量 (400千卡/天) 或全肠道养.
- 没有呼吸机的日期到28日是主要的结果指标.
主要成果:
- 摄食组和全食组之间没有观察到无呼吸器日 (14.9 vs 15.0) 或60天死亡率 (23.2% vs 22.2%) 的显著差异.
- 完全养组在最初的6天内获得的卡路里量 (每天1300卡路里,每天400卡路里) 大大增加了.
- 胃肠道不耐受性,包括吐,胃残留体积增加和便秘,在全养组显著高于全养组.
结论:
- 与全养相比,ALI患者的初始热带肠道养不会改善无呼吸器日或降低死亡率.
- 在ALI管理的初始阶段,多性食与胃肠不耐受性降低有关.
- 进一步的研究可能会探索ALI中肠道营养的最佳时间和进展.
更多相关视频
04:53A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
10.1K
04:10Non-Invasive Endotracheal Administration of Lipopolysaccharide to Induce Acute Lung Injury in Rodents
Published on: December 5, 2025
495
相关概念视频
Pneumonia V: Nursing management and Prevention
4.2K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
4.2K
Acute Respiratory Failure-V
773
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
773
Endotracheal Intubation I: Procedure
14.0K
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
14.0K
Endotracheal Intubation II: Nursing Management
3.8K
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
3.8K
Enteral Nutrition I: Orogastric and Nasogastric Feeding
3.1K
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
3.1K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
2.0K
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
2.0K
