相关实验视频

Updated: May 25, 2026

Ubiquitin Chain Analysis by Parallel Reaction Monitoring
08:33

Ubiquitin Chain Analysis by Parallel Reaction Monitoring

Published on: June 17, 2020

从NMR和小角度散射数据的整体分析中,对尿素和展开的泛素之间的相互作用进行了序列特定的映射

Jie-rong Huang1, Frank Gabel, Malene Ringkjøbing Jensen

  • 1CEA, Institut de Biologie Structurale Jean-Pierre Ebel, 41 Rue Jules Horowitz, Grenoble 38027, France.

Journal of the American Chemical Society
|February 8, 2012
PubMed
概括

尿素通过直接与蛋白质骨干结合而使蛋白质变质. 这项研究表明,30-40%的类组结合尿素,揭示了序列特异性相互作用,这对于理解蛋白质变性至关重要.

更多相关视频

Detection of Protein Ubiquitination Sites by Peptide Enrichment and Mass Spectrometry11:54

Detection of Protein Ubiquitination Sites by Peptide Enrichment and Mass Spectrometry

Published on: March 23, 2020

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry07:33

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

相关概念视频

Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein.