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Updated: May 24, 2026

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
19:44

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

Published on: May 30, 2012

在依赖KRAS的结肠癌中,TAK1抑制促进了亡

Anurag Singh1, Michael F Sweeney, Min Yu

  • 1Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA.

Cell
|February 21, 2012
PubMed
概括

向TAK1激酶 (MAP3K7) 为KRAS突变结肠癌提供了一个新的治疗策略. 这种激酶通过抑制Wnt信号,对瘤细胞存活至关重要,从而呈现出一种潜在的治疗途径.

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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

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