肝细胞癌是肝细胞癌
Alejandro Forner1, Josep M Llovet, Jordi Bruix
1Barcelona Clinic Liver Cancer group, Liver Unit, Hospital Clínic Barcelona, August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain.
Lancet (London, England)
|February 23, 2012
概括
通过超声波监测肝细胞癌的监测有助于早期检测潜在的治疗方法,如切除或移植. 晚期病例可能受益于化学栓塞或分子向疗法,改善生存率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 肝细胞癌 (HCC) 是全球癌症死亡的主要原因.
- 肝硬化显著增加了发展HCC的风险.
- 通过定期查进行早期检测对于改善患者的治疗结果至关重要.
研究的目的:
- 审查目前对肝细胞癌的监测策略.
- 根据疾病阶段讨论HCC的各种治疗方法.
- 突出HCC管理和正在进行的研究方面的进展.
主要方法:
- 对HCC监测当前临床指南的审查.
- 对切除,肝移植,切除和化学栓塞的治疗结果的分析.
- 在先进的HCC中评估分子向疗法的证据.
主要成果:
- 对高风险患者 (肝硬化) 建议每六个月进行一次超声波检查.
- 治愈治疗 (切除,移植,切除) 对早期瘤最有效.
- 化学栓塞和索拉费尼布 (分子向疗法) 在晚期或耐化学性HCC中显示出生存益处.
结论:
- 通过监测早期发现肝细胞癌可以提高治愈能力和生存率.
- 治疗选择取决于瘤特征,肝功能和患者的资格.
- 目前正在进行的致病和向治疗的研究对未来的HCC管理具有前景.
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