一个药剂师领导的信息技术干预药物错误 (PINCER):一个多中心,集群随机,受控试验和成本效益分析
Anthony J Avery1, Sarah Rodgers, Judith A Cantrill
1Division of Primary Care, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, UK. tony.avery@nottingham.ac.uk
Lancet (London, England)
|February 24, 2012
概括
药剂师主导的IT干预 (PINCER) 显著减少了初级保健中的药物错误. 这种方法被证明是具有成本效益的,通过尽量减少危险的处方和确保适当的监测来提高患者安全.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 患者安全 患者安全
- 临床药房 临床药房
背景情况:
- 在初级保健中,药物错误很普遍,对患者的健康构成重大风险.
- 一个由药剂师领导的,基于信息技术的干预措施被评估与简单的反来减少与药物相关的风险.
研究的目的:
- 评估PINCER干预措施在减少药物错误方面的有效性.
- 将PINCER干预与初级保健机构的标准反进行比较.
主要方法:
- 一个务实的,集群随机试验,涉及英国的一般做法.
- 实践被分配到计算机生成的反或PINCER干预 (反,教育宣传,专用支持).
- 在6个月测量的主要结果包括与NSAID,β-阻断剂和ACE抑制剂/利尿剂相关的特定处方错误.
主要成果:
- 在PINCER组的患者中,NSAIDs的危险处方率显著降低 (OR 0.58) 和喘患者的β-阻断剂 (OR 0.73).
- 老年患者的ACE抑制剂或循环利尿剂的监测错误也在PINCER组显著减少 (OR 0.51).
- 这项干预表明,成本效益的可能性很高.
结论:
- PINCER干预是一个有效的策略,用于减少一般实践中的药物错误.
- 这种由药剂师主导的基于IT的方法通过改进的处方和监测实践来提高患者的安全性.
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