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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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对COPII外衣尺寸和功能的乌比奎丁依赖调节

Lingyan Jin1, Kanika Bajaj Pahuja, Katherine E Wickliffe

  • 1Department of Molecular and Cell Biology, University of California at Berkeley, California 94720, USA.

Nature
|February 24, 2012
PubMed
概括

乌比基酸酶CUL3-KLHL12单双基酸盐SEC31,使得像原蛋白这样的重货物可以有更大的COPII囊层. 这一发现解释了COPII囊泡大小是如何调节有效的蛋白质分泌的.

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