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相关概念视频

The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

OverviewElements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Minerals01:26

Minerals

Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Mutagenicity and Carcinogenicity01:25

Mutagenicity and Carcinogenicity

Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...

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相关实验视频

Updated: May 24, 2026

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
17:28

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

和人类健康

Margaret P Rayman1

  • 1Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK. m.rayman@surrey.ac.uk

Lancet (London, England)
|March 3, 2012
PubMed
概括

对健康至关重要,影响免疫力,生殖和甲状腺功能. 然而,补充剂可能会伤害那些有足够水平的人,突出了U形的健康益处.

科学领域:

  • 生物化学 生物化学
  • 人类健康 人类健康 人类健康
  • 营养科学 营养科学

背景情况:

  • 是蛋白质的组成部分,影响抗氧化,抗炎和甲状腺激素的产生.
  • 最近的发现将蛋白基因多态与疾病联系起来,强调了对健康的重要意义.
  • 低状态与死亡率增加,免疫力受损和认知能力下降有关.

研究的目的:

  • 审查的性作用及其在各种健康结果中的作用.
  • 检查状况与慢性疾病风险 (包括癌症和糖尿病) 之间的关联.
  • 阐明状态与健康益处或不良影响之间的U形关系.

主要方法:

  • 对的生物化学功能研究的文献综述.
  • 对连接状态与疾病风险的流行病学数据的分析.
  • 对补充剂临床试验结果的评估.

主要成果:

  • 充足的状态对于免疫功能,生殖和甲状腺健康至关重要,具有潜在的抗病毒作用.
  • 较高的状态可能会降低某些癌症的风险,但试验结果是混合的.
  • 摄入足够的的个人补充可能会增加2型糖尿病的风险.

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High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
11:38

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)

Published on: May 10, 2016

相关实验视频

Last Updated: May 24, 2026

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
17:28

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans
10:55

Comprehensive Assessment of Germline Chemical Toxicity Using the Nematode Caenorhabditis elegans

Published on: February 22, 2015

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
11:38

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)

Published on: May 10, 2016

结论:

  • 对健康的影响呈现出U形的剂量反应曲线,强调状态超过补充剂.
  • 由于潜在的不良影响,具有充足或高水平的个人应避免补充.
  • 保持最佳的状态是关键,补充剂只对那些有记录不足的人有益.