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Updated: May 24, 2026

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer
08:29

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer

Published on: November 1, 2019

识别SUMO修饰的PCNA需要Srs2中的并联受体动机

Anthony A Armstrong1, Firaz Mohideen, Christopher D Lima

  • 1Structural Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.

Nature
|March 3, 2012
PubMed
概括

乌比奎丁 (Ub) 和SUMO (Smt3) 修改了细胞信号传递的蛋白质. 研究人员发现,Srs2螺旋酶使用两个动机来特别识别SUMO修饰的PCNA,这对于DNA修复途径至关重要.

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