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相关概念视频

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
The Retina01:32

The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.

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相关实验视频

Updated: May 24, 2026

Reconstruct Human Retinoblastoma In Vitro
06:52

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

视网母细胞瘤是一种视网母细胞瘤.

Helen Dimaras1, Kahaki Kimani, Elizabeth A O Dimba

  • 1Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.

Lancet (London, England)
|March 15, 2012
PubMed
概括
此摘要是机器生成的。

视网母细胞瘤是一种侵袭性的儿童眼部癌症,在低收入国家死亡率很高. 全球数字通信和遗传技术为改善护理和减少死亡提供了机会.

更多相关视频

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
07:55

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

相关实验视频

Last Updated: May 24, 2026

Reconstruct Human Retinoblastoma In Vitro
06:52

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
07:55

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

科学领域:

  • 在瘤学瘤学.
  • 眼科医生 眼科 眼科
  • 遗传学 是一个遗传学.

背景情况:

  • 视网母细胞瘤是一种严重的婴儿和儿童眼部癌症,根据呈现的严重程度,其存活率可变.
  • 尽管了解了其遗传起源,但在低收入和中等收入国家,死亡率仍然很高 (约为70%).
  • 由于公众/医疗意识较低,以及缺乏创新治疗方法的临床试验,这一进展受到阻碍.

研究的目的:

  • 为了突出视网膜母细胞瘤结果的全球差异.
  • 探索数字通信和先进技术在改善护理标准方面的潜力.
  • 倡导提高认识,进行基因检测和合作研究,以减少死亡率.

主要方法:

  • 审查当前在视网膜母细胞瘤管理方面的挑战.
  • 识别全球数字通信所带来的机会.
  • 强调利用基因组级技术进行基因检测.
  • 推广最佳实践指南,数据共享和临床试验.

主要成果:

  • 据估计,每年约有9000例新病例面临高死亡率,特别是在资源有限的环境中.
  • 数字通信为全球优化护理标准提供了一个平台.
  • 父母倡导对于提高人们对白血病等早期症状的认识至关重要.
  • 基因组技术可以为受影响家庭提供广泛的基因测试.

结论:

  • 改善视网膜母细胞瘤存活率需要采取多方面的方法,包括提高认识和可访问的基因测试.
  • 通过数字平台和严格的研究进行全球合作对于降低死亡率至关重要.
  • 通过幸存者和家庭参与,优先考虑儿童的整体福祉至关重要.