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Updated: May 24, 2026

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
11:19

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

Published on: February 25, 2011

在缺少密码子的情况下,在核糖体中通过tmRNA和SmpB进行解码

Cajetan Neubauer1, Reynald Gillet, Ann C Kelley

  • 1Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, UK.

Science (New York, N.Y.)
|March 17, 2012
PubMed
概括

细菌停滞的核糖体被转移信使RNA (tmRNA) 和SmpB蛋白所拯救. 晶体结构揭示了SmpB如何模仿tRNA和mRNA,在不破坏正常翻译的情况下促进救援.

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