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Updated: May 7, 2026

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小分子抑制剂的AAA+ ATPase电机细胞质二烯

Ari J Firestone1, Joshua S Weinger, Maria Maldonado

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|March 20, 2012
PubMed
概括

研究人员发现了 ciliobrevins,这是第一个特定的小分子对抗细胞质dynein (运动蛋白质) 的第一个特定的小分子对抗剂. 这些化合物扰乱了由丁氨酸调节的细胞过程,为生物研究提供了新的工具.

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